Captain America and The Avengers is based on the 1991 Data East arcade game. Players can choose between four characters: Captain America, Iron Man, Hawkeye or Vision as they punch, kick, or use special powers to dispose of various enemies. Along the way characters will be able to pick up trash cans or other objects to throw at the enemy. While the game is primarily a side-scrolling beat 'em up, there are also shooting stages that will find your character flying through the air or swimming under water. In addition, two players can play simultaneously on one of three difficulty levels.

The Red Skull believes he can take over the world with the help of super-villains Whirlwind, Living Laser, Klaw, Grim Reaper, and various other unsavory types. Trouble is, they happen to enjoy working alone. So after careful planning and research, Red Skull came up with an invention to bring all of the twisted criminals under one power: a mind-control device. Now Captain America and The Avengers must not only unite to stop their arch-enemies from wreaking havoc upon the world, but somehow find Red Skull's secret device and put an end to his diabolical plans. ~ Scott Alan Marriott, All Game Guide