Description taken from Nintendo GameCube version of this game

Inspired by 2003's one-hour television special starring Nickelodeon's masterminding moppet, The Adventures of Jimmy Neutron finds players on a quest to rescue the boy genius' favorite spy, Jet Fusion. It seems the diabolical Professor Calamitous has abducted the secret agent in a newly remodeled Retroville. To save the world and his admired operative, Jimmy Neutron must once again tap into his arsenal of resourceful gadgets to advance through deserts, seas, and forests. In addition to jumping platforms, confronting enemies, and solving puzzles, players will be able to watch clips from the television special to help further the storyline. ~ Scott Alan Marriott, All Game Guide